Product Type: Antibody
Descritpion: This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Research Areas: Cancer, Signal transduction
Recommended Dilutions: WB 1:200-1:1000, IHC 1:25-1:100
Size: 200 uL
Gene Accession: BC002869
Immunogen: Recombinant protein of human STXBP2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 66kDa
Tissue Specificity/Positive Control: Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.
Cellular Localization: Cytosol,Extracellular region or secreted,extracellular exosome,extracellular region,Lysosome,azurophil granule,cytolytic granule,Plasma Membrane,apical Plasma Membrane,Other locations:phagocytic vesicle,specific granule,tertiary granule,zymogen granule membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.