ABCB6 Polyclonal AntibodyE-AB-14457
Product Type: Antibody
Descritpion: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
Research Areas: Cancer, Cardiovascular, Metabolism, Signal transduction
Recommended Dilutions: WB 1:200-1:1000
Size: 200 uL
Gene Accession: BC000559
Immunogen: Recombinant protein of human ABCB6
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 94kDa
Tissue Specificity/Positive Control: Widely expressed. Highest expression in heart and skeletal muscles.
Cellular Localization: Mitochondrion outer membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-abcb6_polyclonal_antibody-33885.html
Manual Link: https://www.elabscience.com/viewpdf-33885-elabscience-E-AB-14457.PDF