Product Type: Antibody
Descritpion: This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction. Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Research Areas: Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:25-1:100
Size: 200 uL
Gene Accession: BC025372
Immunogen: Recombinant protein of human CNN3
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 36kDa
Tissue Specificity/Positive Control: Expressed in both non-smooth muscle tissues as well as smooth muscle tissues.
Cellular Localization: Cytoskeleton,actin cytoskeleton,Cytosol,Other locations:cell-cell adherens junction,dendritic spine,focal adhesion,neuronal cell body,postsynaptic density
Storage: Store at -20C. Avoid freeze / thaw cycles.