ACTL7B Polyclonal AntibodyE-AB-14488
Product Type: Antibody
Descritpion: The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia.
Research Areas: Signal transduction
Recommended Dilutions: IHC 1:15-1:50
Size: 200 uL
Gene Accession: BC033789
Immunogen: Recombinant protein of human ACTL7B
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Detected only in the testis and, to a lesser extent, in the prostate.
Cellular Localization: Cytoplasm>cytoskeleton.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-actl7b_polyclonal_antibody-33916.html
Manual Link: https://www.elabscience.com/viewpdf-33916-elabscience-E-AB-14488.PDF