ADAMTSL2 Polyclonal AntibodyE-AB-14505
Product Type: Antibody
Descritpion: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia.
Research Areas: Developmental biology, Signal transduction
Recommended Dilutions: WB 1:200-1:1000
Size: 200 uL
Gene Accession: BC050544
Immunogen: Recombinant protein of human ADAMTSL2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 105kDa
Tissue Specificity/Positive Control:
Cellular Localization: Secreted.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-adamtsl2_polyclonal_antibody-33933.html
Manual Link: https://www.elabscience.com/viewpdf-33933-elabscience-E-AB-14505.PDF