Product Type: Antibody
Descritpion: Metallocarboxypeptidase that may play a role in the processing of tubulin. Knockdown of AGBL2 results in a failure of the cell to detyrosinate the C-terminal EEY region of ?-tubulin and indicates that, it is a candidate for the long sought after tubulin tyrosine carboxypeptidase important in regulation of microtubule dynamics. RARRES1, its interacting partners AGBL2, Eg5/KIF11, another EEY bearing protein (EB1), and the microtubule tyrosination cycle are important in tumorigenesis and identify a novel area for therapeutic intervention.
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: BC028200
Immunogen: Recombinant protein of human AGBL2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control:
Cellular Localization: Cytoskeleton,centriole,ciliary basal body,Cytosol
Storage: Store at -20C. Avoid freeze / thaw cycles.