Product Type: Antibody
Descritpion: A-kinase anchor protein 8-like is an enzyme that in humans is encoded by the AKAP8L gene. Could play a role in constitutive transport element (CTE)-mediated gene expression. Does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May regulate the initiation phase of DNA replication when associated with TMPO-beta.
Research Areas: Epigenetics and Nuclear Signaling
Recommended Dilutions: WB 1:200-1:1000, IHC 1:25-1:100
Size: 200 uL
Gene Accession: BC000713
Immunogen: Recombinant protein of human AKAP8L
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 72kDa
Tissue Specificity/Positive Control: Ubiquitously expressed. Expressed in the brain cortex (at protein level).
Cellular Localization: Nuclear matrix. Cytoplasm. Note=Nuclear at steady state but shuttles between the nucleus and cytoplasm. Associated with the nuclear matrix.
Storage: Store at -20C. Avoid freeze / thaw cycles.