SERPINA3 Polyclonal AntibodyE-AB-14544
Product Type: Antibody
Descritpion: The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
Research Areas: Cancer, Cell Biology, Cardiovascular, Neuroscience
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: BC034554
Immunogen: Recombinant protein of human SERPINA3
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains.
Cellular Localization: Secreted.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-serpina3_polyclonal_antibody-33972.html
Manual Link: https://www.elabscience.com/viewpdf-33972-elabscience-E-AB-14544.PDF