Product Type: Antibody
Descritpion: The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact.
Research Areas: Immunology, Signal transduction
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC005830
Immunogen: Recombinant protein of human ANXA9
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level).
Cellular Localization: Cytosol,Extracellular region or secreted,extracellular exosome,Other locations:cell surface
Storage: Store at -20C. Avoid freeze / thaw cycles.