Product Type: Antibody
Descritpion: The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.
Research Areas: Signal transduction
Recommended Dilutions: WB 1:1000-1:5000, IHC 1:25-1:100
Size: 200 uL
Gene Accession: BC028233
Immunogen: Recombinant protein of human ARFGAP1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 45kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytoplasm. Golgi apparatus. Associates with the Golgi complex.
Storage: Store at -20C. Avoid freeze / thaw cycles.