SETD2 Polyclonal Antibody
SETD2 Polyclonal Antibody

SETD2 Polyclonal Antibody

E-AB-14627

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Concentration: 0.2mg/mL
Swissprot: Q9BYW2
Gene Accession: BC117162
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human SETD2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Ubiquitously expressed.
Cellular Localization: Nucleus. Chromosome.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-setd2_polyclonal_antibody-34055.html
Manual Link: https://www.elabscience.com/viewpdf-34055-elabscience-E-AB-14627.PDF