Product Type: Antibody
Descritpion: This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16.
Research Areas: Cell Biology, Epigenetics and Nuclear Signaling
Recommended Dilutions: WB 1:1000-1:5000, IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC000703
Immunogen: Recombinant protein of human CDCA8
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 31kDa
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus>nucleolus. Cytoplasm. Cytoplasm>cytoskeleton>spindle. Chromosome>centromere. Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with SENP3 in the nucleolus in interphase cells.
Storage: Store at -20C. Avoid freeze / thaw cycles.