Product Type: Antibody
Descritpion: Epidermal growth factor receptor substrate 15-like 1 is a protein that in humans is encoded by the EPS15L1gene. EPS15L1 has been shown to interact with HRB. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.
Research Areas: Cancer, Signal transduction
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: BC131590
Immunogen: Recombinant protein of human EPS15L1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control:
Cellular Localization: Cell membrane. Nucleus. Membrane>coated pit. Localized to plasma membrane coated pits.
Storage: Store at -20C. Avoid freeze / thaw cycles.