Product Type: Antibody
Descritpion: NIF3L1 BP1 (Ngg1-interacting factor 3-like 1 binding protein 1), also known as THOC7 (THO complex subunit 7 homolog), fSAP24 or hTREX30, is a 204 amino acid cytoplasmic and nuclear protein that belongs to the THOC7 family and interacts with NIF3L1. NIF3L1 BP1 is a component of the THO/TREX complex that is recruited to transcribed genes and travels along with RNA polymerase II (Pol II) during elongation, coupling Pol II with RNA splicing and export factors. The THO/TREX complex also plays a role in the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The gene that encodes NIF3L1 BP1 maps to human chromosome 3p14.1.
Research Areas: Epigenetics and Nuclear Signaling
Recommended Dilutions: WB 1:500-1:2000, IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC065012
Immunogen: Recombinant protein of human THOC7
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 24kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytoplasm. Nucleus. Interaction with THOC5 is required for nuclear localization.
Storage: Store at -20C. Avoid freeze / thaw cycles.