BMI1 Polyclonal AntibodyE-AB-14728
Product Type: Antibody
Descritpion: BMI1 polycomb ring finger oncogene, also known as BMI1, is a protein which in humans is encoded by the BMI1gene. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Stem cells
Recommended Dilutions: WB 1:200-1:1000
Size: 200 uL
Gene Accession: BC011652
Immunogen: Recombinant protein of human BMI1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 37kDa
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus. Cytoplasm.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-bmi1_polyclonal_antibody-34156.html
Manual Link: https://www.elabscience.com/viewpdf-34156-elabscience-E-AB-14728.PDF