ACLY Polyclonal AntibodyE-AB-14775
Product Type: Antibody
Descritpion: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.
Research Areas: Cancer, Metabolism, Signal transduction
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Gene Accession: BC006195
Immunogen: Recombinant protein of human ACLY
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 121kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytoplasm.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-acly_polyclonal_antibody-34203.html
Manual Link: https://www.elabscience.com/viewpdf-34203-elabscience-E-AB-14775.PDF