Product Type: Antibody
Descritpion: This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.
Research Areas: Cardiovascular
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC003135
Immunogen: Recombinant protein of human KEL
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Expressed at high levels in erythrocytes and testis (in Sertoli cells), and, at lower levels, in skeletal muscle, tonsils (in follicular dendritic cells), lymph node, spleen and appendix (at protein level). Also expressed in many adult and fetal nonerythroid tissues, including brain, spleen, lymph nodes and bone marrow.
Cellular Localization: Cell membrane. Spans the erythrocyte membrane, and is attached to the underlying cytoskeleton.
Storage: Store at -20C. Avoid freeze / thaw cycles.