BAZ1A Polyclonal AntibodyE-AB-15897
Product Type: Antibody
Descritpion: Bromodomain adjacent to zinc finger domain protein 1A is a protein that in humans is encoded by the BAZ1A gene. Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase.
Research Areas: Epigenetics and Nuclear Signaling
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_038476
Immunogen: Synthetic peptide of human BAZ1A
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Highly expressed in testis and at low or undetectable levels in other tissues analyzed.
Cellular Localization: Nucleus. May target the CHRAC complex to heterochromatin.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-baz1a_polyclonal_antibody-35295.html
Manual Link: https://www.elabscience.com/viewpdf-35295-elabscience-E-AB-15897.PDF