Anti-Human CD47 Monoclonal Antibody (PE/Cy5 Conjugated)E-AB-1613
Product Type: monoclonal antibody for FC
Description: CD47 antigen, also known as integrin-associated protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells. B6H12 antibody is capable of blocking phagocytosis of microparticles by peripheral blood granulocytes. It has also been reported to induce proliferation of CD3-activated T cells.
Resarch Areas: Cancer, Immunology
Clone No: B6H12
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used from 20 µL to 5 µL per 100 µL of peripheral blood or 10^6 cells in 100 µl. Please check your vial). Since applications vary, the appropriate dilutions must be determined for individual use.
Isotype: Mouse IgG1
Formulation: PBS with 0.09% NaN3, 0.2% BSA, PH7.2
Storage: Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.
Product Link: https://www.elabscience.com/p-anti_human_cd47_monoclonal_antibody_(pe_cy5_conjugated)-39097.html
Manual Link: https://www.elabscience.com/viewpdf-39097-elabscience-E-AB-1613.PDF