APBA1 Polyclonal AntibodyE-AB-16162
Product Type: Antibody
Descritpion: The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
Research Areas: Neuroscience
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Gene Accession: NP_001154
Immunogen: Synthetic peptide of human APBA1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 93kDa
Tissue Specificity/Positive Control: Brain and spinal cord.
Cellular Localization: Cytosol,Golgi apparatus,Golgi apparatus,Nucleus,Other locations:membrane,neuron projection,perinuclear region of cytoplasm,synaptic vesicle
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-apba1_polyclonal_antibody-35559.html
Manual Link: https://www.elabscience.com/viewpdf-35559-elabscience-E-AB-16162.PDF