Product Type: Antibody
Descritpion: Phosphoinositide 3-kinase regulatory subunit 4, also known as PI3-kinase regulatory subunit 4 or PI3-kinase p150 subunit or phosphoinositide 3-kinase adaptor protein, or VPS15 is an enzyme that in humans is encoded by the PIK3R4 gene. The PI3-kinases regulate cellular signaling networks that are involved in processes linked to the survival, growth, proliferation, metabolism and specialized differentiated functions of cells. The subversion of this network is common in cancer and has also been linked to disorders of inflammation.
Research Areas: Cancer, Signal transduction
Recommended Dilutions: IHC 1:100-1:300
Size: 200 uL
Gene Accession: NP_055417
Immunogen: Synthetic peptide of human PIK3R4
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Ubiquitously expressed.
Cellular Localization: Cytoskeleton,axoneme,microtubule cytoskeleton,Cytosol,Endosome,late endosome,Nucleus,nuclear pore,Other locations:autophagosome,intracellular membrane-bounded organelle,membrane,nucleus-vacuole junction,phagocytic vesicle membrane,phosphatidylinositol 3-kinase complex, class III,phosphatidylinositol 3-kinase complex, class III, type I,phosphatidylinositol 3-kinase complex, class III, type II
Storage: Store at -20C. Avoid freeze / thaw cycles.