Product Type: Antibody
Descritpion: Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
Research Areas: Cell Biology, Epigenetics and Nuclear Signaling, Neuroscience
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: NP_056154
Immunogen: Synthetic peptide of human ADNP
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues.
Cellular Localization: Extracellular region or secreted,extracellular space,Nucleus,Other locations:axon,cytoplasm,dendrite,neuronal cell body
Storage: Store at -20C. Avoid freeze / thaw cycles.