Product Type: Antibody
Descritpion: The gene encoding BCAS4 (Breast carcinoma-amplified sequence 4), a 211 amino acid protein, is found in a region on chromosome 20 that is frequently amplified in human breast cancer. The amplification and translocation between the BCAS4 gene and the BCAS3 gene, with a 17q23 locus, results in a fusion transcript that is overexpressed in MCF-7 cells. Also, deletion of chromosomal region 20q13.13-q13.2 and resultant deletion of BCAS4, as well as three other genes, is the cause of Okihiro syndrome, a disease characterized by ocular and upper limb anomalies.
Research Areas: Cancer
Recommended Dilutions: WB 1:500-1:2000, IHC 1:50-1:200
Size: 200 uL
Gene Accession: NP_001010974
Immunogen: Synthetic peptide of human BCAS4
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 23kDa
Tissue Specificity/Positive Control: Brain, thymus, spleen, kidney and placenta. Overexpressed in most breast cancer cell lines.
Cellular Localization: Cytoplasm.
Storage: Store at -20C. Avoid freeze / thaw cycles.