Product Type: Antibody
Descritpion: The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300
Size: 200 uL
Gene Accession: NP_004350
Immunogen: Synthetic peptide of human CDC34
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 27kDa
Tissue Specificity/Positive Control: Expressed in testes during spermatogenesis to regulate repression of cAMP-induced transcription.
Cellular Localization: Cytoplasm. Nucleus. The phosphorylation of the C-terminal tail plays an important role in mediating nuclear localization. Colocalizes with beta-tubulin on mitotic spindles in anaphase.
Storage: Store at -20C. Avoid freeze / thaw cycles.