CYP2D6 Polyclonal Antibody
CYP2D6 Polyclonal Antibody

CYP2D6 Polyclonal Antibody

E-AB-16371

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant.
Research Areas: Cardiovascular, Metabolism, Signal transduction
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:200-1:1000, IHC 1:25-1:100
Size: 200 uL
Concentration: 0.9mg/mL
Swissprot: P10635
Gene Accession: NP_000097
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human CYP2D6
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 56kDa
Tissue Specificity/Positive Control:
Cellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-cyp2d6_polyclonal_antibody-35766.html
Manual Link: https://www.elabscience.com/viewpdf-35766-elabscience-E-AB-16371.PDF