DSC2 Polyclonal AntibodyE-AB-16388
Product Type: Antibody
Descritpion: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11.
Research Areas: Cardiovascular, Signal transduction
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_077740
Immunogen: Synthetic peptide of human DSC2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Expressed in epithelia, myocardium and lymph nodes.
Cellular Localization: Cell membrane. Cell junction>desmosome.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-dsc2_polyclonal_antibody-35783.html
Manual Link: https://www.elabscience.com/viewpdf-35783-elabscience-E-AB-16388.PDF