DSG1 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.
Research Areas: Cancer, Signal transduction
Applications: WB,ELISA
Recommended Dilutions: WB 1:200-1:1000
Size: 200 uL
Concentration: 0.4mg/mL
Swissprot: Q02413
Gene Accession: NP_001933
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human DSG1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 114kDa
Tissue Specificity/Positive Control: Epidermis, tongue, tonsil and esophagus.
Cellular Localization: Cell membrane. Cell junction>desmosome.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-dsg1_polyclonal_antibody-35784.html
Manual Link: https://www.elabscience.com/viewpdf-35784-elabscience-E-AB-16389.PDF