LOXL1 Polyclonal Antibody

LOXL1 Polyclonal Antibody

E-AB-16574

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to eacHuman, Mouseember of the family. 
Research Areas: Cell Biology, Metabolism, Signal transduction
Applications: WB,ELISA
Recommended Dilutions: WB 1:200-1:1000
Size: 200 uL
Concentration: 0.3mg/mL
Swissprot: Q08397
Gene Accession: NP_005567
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human LOXL1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 63kDa
Tissue Specificity/Positive Control: Expressed in ocular tissues including the iris, ciliary body, lens and optic nerve. Not detected in the retina.1 Publication
Cellular Localization: Secreted, extracellular space.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-loxl1_polyclonal_antibody-35969.html
Manual Link: https://www.elabscience.com/viewpdf-35969-elabscience-E-AB-16574.PDF