Product Type: Antibody
Descritpion: MFSD2 (major facilitator superfamily domain containing 2), also known as MFSD2A, is a 543 amino acid multi-pass membrane protein of the endoplasmic reticulum that is involved in beta-adrenergic signaling during thermogenesis. Existing as three alternatively spliced isoforms, MFSD2 plays a role in G1 regulation and is encoded by a gene that maps to human chromosome 1p34.2. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
Research Areas: Cancer, Neuroscience
Recommended Dilutions: WB 1:500-1:2000, IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_001129965
Immunogen: Synthetic peptide of human MFSD2A
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 60kDa
Tissue Specificity/Positive Control: In placenta, associated with trophoblast cells.1 Publication
Cellular Localization: Endoplasmic reticulum membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.