Product Type: Antibody
Descritpion: This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. Alternate splicing results in multiple transcript variants that encode the same protein.
Research Areas: Cancer, Immunology
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_002571
Immunogen: Synthetic peptide of human REG3A
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Highly expressed in epidermal keratinocytes of psoriasis patients (at protein level). Constitutively expressed in intestine. Low expression is found in healthy pancreas. Overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis.
Cellular Localization: Secreted. Found in the apical region of pancreatic acinar cells.
Storage: Store at -20C. Avoid freeze / thaw cycles.