Product Type: Antibody
Descritpion: This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: NP_001003794
Immunogen: Synthetic peptide of human MGLL
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Detected in adipose tissue, lung, liver, kidney, brain and heart.
Cellular Localization: Cytosol,Endoplasmic reticulum,endoplasmic reticulum membrane,Nucleus,nucleoplasm,Plasma Membrane,Other locations:extrinsic component of membrane,membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.