Product Type: Antibody
Descritpion: MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. MRGX1 is probably involved in the function of nociceptive neurons and may regulate nociceptor function and/or development, including the sensation or modulation of pain. It is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells.
Research Areas: Signal transduction
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: NP_671732
Immunogen: Synthetic peptide of human MRGPRX1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.1 Publication
Cellular Localization: Cell Membrane; Multi-pass membrane protein.
Storage: Store at -20C. Avoid freeze / thaw cycles.