MT-ND6 Polyclonal Antibody
MT-ND6 Polyclonal Antibody

MT-ND6 Polyclonal Antibody

E-AB-16622

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. The significance of NADH dehydrogenase subunit 6 (ND6) is rapidly becoming increasingly apparent as many mutations leading to amino acid changes in this subunit are associated with known mitochondrial diseases.
Research Areas: Cancer, Metabolism, Neuroscience, Signal transduction
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Concentration: 0.8mg/mL
Swissprot: P03923
Gene Accession: YP_003024037
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human MT-ND6
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control:
Cellular Localization: Mitochondrion membrane; Multi-pass membrane protein.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-mt_nd6_polyclonal_antibody-36017.html
Manual Link: https://www.elabscience.com/viewpdf-36017-elabscience-E-AB-16622.PDF