Product Type: Antibody
Descritpion: Peptidoglycan recognition protein is a protein that in humans is encoded by the PGLYRP1gene. Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
Research Areas: Cancer, Cell Biology, Immunology, Microbiology, Neuroscience
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_005082
Immunogen: Synthetic peptide of human PGLYRP1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils.
Cellular Localization: Secreted. Cytoplasmic granule.
Storage: Store at -20C. Avoid freeze / thaw cycles.