Product Type: Antibody
Descritpion: This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.
Research Areas: Cell Biology
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_002764
Immunogen: Synthetic peptide of human PRSS8
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid.
Cellular Localization: Cell membrane and Secreted>extracellular space. Found in the seminal fluid. Secreted after cleavage of its C-terminus.
Storage: Store at -20C. Avoid freeze / thaw cycles.