Product Type: Antibody
Descritpion: Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs.
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism
Recommended Dilutions: WB 1:200-1:1000, IHC 1:50-1:200
Size: 200 uL
Gene Accession: NP_653310
Immunogen: Synthetic peptide of human PUS10
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 60kDa
Tissue Specificity/Positive Control:
Storage: Store at -20C. Avoid freeze / thaw cycles.