Product Type: Antibody
Descritpion: Sca-1 is an 18 kDa phosphatidylinositol-anchored protein that is a member of the lymphocyte antigen 6 (Ly-6) family. Sca-1 is encoded by the strain-specific Ly-6 E/A allelic gene. Its expression on multipotent hematopoietic stem cells (HSC) has been used as a marker of HSCs in mice of both Ly-6 haplotypes. Sca-1-positive HSCs can be found in the adult bone marrow, fetal liver, and mobilized peripheral blood and spleen in the adult animal.
Research Areas: Developmental biology, Cardiovascular, Stem cells
Recommended Dilutions: WB 1:200-1:1000, IHC 1:50-1:200
Size: 200 uL
Gene Accession: NP_001258345
Immunogen: Synthetic peptide of mouse Ly6a
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 14kDa
Tissue Specificity/Positive Control: Widely expressed.
Cellular Localization: Plasma Membrane,external side of plasma membrane,Other locations:anchored component of membrane,intracellular
Storage: Store at -20C. Avoid freeze / thaw cycles.