TREM2 Polyclonal AntibodyE-AB-16947
Product Type: Antibody
Descritpion: This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).
Research Areas: Cancer, Immunology
Recommended Dilutions: WB 1:200-1:1000
Size: 200 uL
Gene Accession: NP_061838
Immunogen: Synthetic peptide of human TREM2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 25kDa
Tissue Specificity/Positive Control: Expressed on macrophages and dendritic cells but not on granulocytes or monocytes. In the CNS strongest expression seen in the basal ganglia, corpus callosum, medulla oblongata and spinal cord.
Cellular Localization: Secreted and Cell membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-trem2_polyclonal_antibody-36342.html
Manual Link: https://www.elabscience.com/viewpdf-36342-elabscience-E-AB-16947.PDF