CENPM Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).
Research Areas:
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:10-50, ELISA 1:1000-2000
Size: 200 uL
Concentration: 0.3mg/mL
Swissprot: Q9NSP4
Gene Accession: BC000705
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Full length fusion protein
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Isoform 3 is highly expressed in spleen, and intermediately in heart, prostate and ovary. Isoform 3 is highly expressed in resting CD19 B-cells and B-lineage chronic lymphocytic leukemia (B-CLL) cells and weakly expressed in activated B-cells. Isoform 1 is selectively expressed in activated CD19 cells and weakly in resting CD19 B-cells.
Cellular Localization: Cytosol,Nucleus,nucleoplasm,Other locations:condensed chromosome kinetochore
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-cenpm_polyclonal_antibody-36377.html
Manual Link: https://www.elabscience.com/viewpdf-36377-elabscience-E-AB-16982.PDF