ECE2 Polyclonal Antibody
ECE2 Polyclonal Antibody

ECE2 Polyclonal Antibody

E-AB-16986

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants. 
Research Areas: Cardiovascular, Neuroscience, Signal transduction
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:500-2000, IHC 1:30-150, ELISA 1:2000-5000
Size: 200 uL
Concentration: 0.4mg/mL
Swissprot: O60344
Gene Accession: BC005835
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Fusion protein of human ECE2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 100 kDa
Tissue Specificity/Positive Control: Expressed in brain. Strongly down-regulated in inferior parietal lobe from Alzheimer disease patients (at protein level).
Cellular Localization: Golgi apparatus membrane. Cytoplasmic granule membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-ece2_polyclonal_antibody-36381.html
Manual Link: https://www.elabscience.com/viewpdf-36381-elabscience-E-AB-16986.PDF