MAPKAPK5 Polyclonal AntibodyE-AB-16989
Product Type: Antibody
Descritpion: The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.
Research Areas: Cancer
Recommended Dilutions: IHC 1:30-150, ELISA 1:2000-10000
Size: 200 uL
Gene Accession: BC041049
Immunogen: Fusion protein of human MAPKAPK5
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Expressed ubiquitously.
Cellular Localization: Cytoplasm. Nucleus. Also observed in the nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-mapkapk5_polyclonal_antibody-36384.html
Manual Link: https://www.elabscience.com/viewpdf-36384-elabscience-E-AB-16989.PDF