UBE2B Polyclonal AntibodyE-AB-17189
Product Type: Antibody
Descritpion: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism
Recommended Dilutions: IHC 1:25-100, ELISA 1:2000-5000
Size: 200 uL
Gene Accession: BC005979
Immunogen: Full length fusion protein
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control:
Cellular Localization: Cell membrane. Nucleus. In peripheral neurons, expressed both at the plasma membrane and in nuclei.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-ube2b_polyclonal_antibody-36584.html
Manual Link: https://www.elabscience.com/viewpdf-36584-elabscience-E-AB-17189.PDF