VPS33B Polyclonal Antibody
VPS33B Polyclonal Antibody

VPS33B Polyclonal Antibody

E-AB-17277

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants.
Research Areas: Signal transduction
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:25-100, ELISA 1:2000-5000
Size: 200 uL
Concentration: 0.6mg/mL
Swissprot: Q9H267
Gene Accession: BC016445
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Fusion protein of human VPS33B
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Ubiquitous; highly expressed in testis and low expression in the lung.
Cellular Localization: Endosome,early endosome membrane,late endosome,late endosome membrane,recycling endosome,Golgi apparatus,Golgi apparatus,Lysosome,lysosomal membrane,lysosome,Other locations:clathrin-coated vesicle,cytoplasm,perinuclear region of cytoplasm,platelet alpha granule
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-vps33b_polyclonal_antibody-36672.html
Manual Link: https://www.elabscience.com/viewpdf-36672-elabscience-E-AB-17277.PDF