Product Type: Antibody
Descritpion: The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus.
Recommended Dilutions: WB 1:200-1000, IHC 1:10-50, ELISA 1:1000-2000
Size: 200 uL
Gene Accession: NP_683763
Immunogen: Synthetic peptide of human CLDN19
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 23 kDa
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus,Plasma Membrane,basolateral plasma membrane,Other locations:apical junction complex,bicellular tight junction,cytoplasm,integral component of membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.