Product Type: Antibody
Descritpion: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells.
Research Areas: Cancer, Metabolism
Recommended Dilutions: WB 1:200-1000, IHC 1:10-50, ELISA 1:1000-2000
Size: 200 uL
Gene Accession: NP_003346
Immunogen: Synthetic peptide of human UCP2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 33 kDa
Tissue Specificity/Positive Control: Widely expressed in adult human tissues, including tissues rich in macrophages. Most expressed in white adipose tissue and skeletal muscle.
Cellular Localization: Mitochondrion inner membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.