Product Type: Antibody
Descritpion: This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known.
Research Areas: Cancer, Neuroscience, Signal transduction
Recommended Dilutions: WB 1:200-1000, IHC 1:30-150, ELISA 1:1000-2000
Size: 200 uL
Gene Accession: NP_003369
Immunogen: Synthetic peptide of human VGF
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 67 kDa
Tissue Specificity/Positive Control: Central and peripheral nervous systems, synthesized exclusively in neuronal and neuroendocrine cells.
Cellular Localization: Secreted. Cytoplasmic vesicle>secretory vesicle. Stored in secretory vesicles and then secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus.
Storage: Store at -20C. Avoid freeze / thaw cycles.