Product Type: Antibody
Descritpion: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Areas: Cancer, Signal transduction
Recommended Dilutions: WB 1:500-2000, IHC 1:30-150, ELISA 1:2000-5000
Size: 200 uL
Gene Accession: NP_004887
Immunogen: Synthetic peptide of human VPS26A
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 38 kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytoplasm. Endosome membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.