Product Type: Antibody
Descritpion: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
Research Areas: Cancer, Cell Biology, Cardiovascular, Signal transduction, Tags & Cell Markers
Recommended Dilutions: IHC 1:25-100, ELISA 1:2000-5000
Size: 200 uL
Gene Accession: NP_008919
Immunogen: Synthetic peptide of human ADAMTS1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control:
Cellular Localization: Secreted>extracellular space>extracellular matrix.
Storage: Store at -20C. Avoid freeze / thaw cycles.