COLEC12 Polyclonal Antibody
COLEC12 Polyclonal Antibody

COLEC12 Polyclonal Antibody

E-AB-17717

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.
Research Areas: Cardiovascular, Immunology, Microbiology, Neuroscience
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:10-50, ELISA 1:1000-2000
Size: 200 uL
Concentration: 0.4mg/mL
Swissprot: Q5KU26
Gene Accession: NP_569057
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human COLEC12
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Expressed in perivascular macrophages. Expressed in plaques-surrounding reactive astrocytes and in perivascular astrocytes associated with cerebral amyloid angiopathy (CAA) in the temporal cortex of Alzheimer patient (at protein level). Strongly expressed in placenta. Moderately expressed in heart, skeletal muscle, small intestine and lung. Weakly expressed in brain, colon, thymus and kidney. Expressed in nurse-like cells. Expressed in reactive astrocytes and vascular/perivascular cells in the brain of Alzheimer patient.
Cellular Localization: Membrane. Forms clusters on the cell surface.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-colec12_polyclonal_antibody-37113.html
Manual Link: https://www.elabscience.com/viewpdf-37113-elabscience-E-AB-17717.PDF