Phospho-Histone H3 (Ser10) Polyclonal Antibody

Phospho-Histone H3 (Ser10) Polyclonal Antibody

E-AB-20891

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,IHC-p,IF,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Clonality: Polyclonal
Clone No:
SwissProt: P68431,Q71DI3,P84243
Gene ID: 8350/8351/8352/8353/8354/8355/8356/8357/8358/8968
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human Histone H3 around the phosphorylation site of Ser10
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 15kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Extracellular region or secreted,extracellular exosome,extracellular region,Nucleus,nuclear chromosome,nuclear chromosome, telomeric region,nuclear nucleosome,nucleoplasm,nucleus,Other locations:nucleosome,protein complex

Product Link: https://www.elabscience.com/p-phospho_histone_h3_(ser10)_polyclonal_antibody-25480.html
Manaul Link: https://www.elabscience.com/viewpdf-25480-elabscience-E-AB-20891.PDF